Study Reveals Reasons Behind Anxiety Disorders, What Is It?
Researchers found the answer to the occurrence of panic attacks or anxiety disorders actually lies in cell power plants, mitochondria. The study was published in the journal PLOS Genetics.
According to researchers, mitochondria provide energy for cellular function. But that activity can be disrupted when chronic stress leads to anxiety symptoms.
Chronic stress due to high pressure or problems, such as divorce, unemployment, loss of loved ones, disputes, etc. are the main factors causing panic attacks and anxiety disorders.
However, not everyone who is stressed has a disorder. Scientists also identified what makes some people resistant to stress, while others are prone to anxiety.
To find the answer, as reported by the website, researchers studied mice that experienced symptoms of anxiety and depression, including avoiding social interaction after experiencing high levels of stress.
They try to track changes in genes and protein production in the brain to respond to stress and anxiety. Analysis shows that there are changes in the mitochondria in the brain cells of mice that are often exposed to stress, in contrast to mice that are not stressed.
In addition, testing of blood samples collected from patients with panic disorder also shows differences in the mitochondrial pathway. This shows that changes in cellular energy metabolism may be a common way for animals to respond to stress.
Research on the effects of high levels of stress on cell power generation functions provides opportunities for new research on stress-related illnesses.
“Very little is known about how chronic stress affects cellular energy metabolism and thus influences anxiety symptoms,” explains the author of Iiris Hovatta, University of Helsinki.
Further studies are needed to determine the causes of mitochondrial changes that can provide knowledge about the molecular basis of panic disorders and other anxiety disorders